Clinical analysis of comorbidities associated with complications from SarsCov2
Keywords:
Comorbidities; COVID-19; clinical severity; meta-analysis.Abstract
The COVID-19 emergency has become a serious global health problem. The identification of comorbidities associated with the severe clinical presentation of COVID-19 is important for the adequate therapeutic approach of affected patients. The objective of this study was to evaluate the risk of COVID-19 with severe clinical presentation in patients with comorbidities. A theoretical, descriptive and documentary-type study design was carried out based on a procedure that involves tracking, organization, systematization and joint analysis of electronic documents on the subject in question, the search strategy was used based on accredited academic profiles to be able to substantiate this article as in the Pubmed database, academic Google, Scielo. Thirdteen studies were included in the analysis. The global effects were obtained for arterial hypertension, cardiovascular disease, Diabetes Mellitus, smoking, chronic respiratory, renal and hepatic diseases and immunodeficiencies, in severe patients compared to non-severe patients. Chronic kidney disease, cardiovascular disease, arterial hypertension and Diabetes Mellitus are among the comorbidities that imply the highest risk for a severe clinical presentation in patients with COVID-19, followed in importance by immunodeficiencies, smoking, chronic respiratory disease and chronic liver disease.
Downloads
References
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. . ( 2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet., 395(10223):497-506.
Liu Y, Yang Y, Zhang C, Huang F, Wang F, Yuan J, et al. (2020). Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. . Sci China Life Sci. , 63(3):364-374.
Amancio A et all. (2021). Relación entre las comorbilidades y la morbilidad y la mortalidad en la COVID-19. Ciencias Biomédicas, http://portal.amelica.org/ameli/jatsRepo/444/4442245026/index.html.
Balibrea JM. . (2020). Manejo quirúrgico de pacientes con infección por COVID-19. Recomendaciones de la Asociación Española de Cirujanos. Cirugia Española. , 98(5).
Cao Y, Li L, Feng Z, Wan S, Huang P, Sun X, et al. . (2020). Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations. Cell Discovery. , 6:11. .
Chow N, Fleming Dutra K, Gierke R, Hall A, Hughes M, Pilishvili T, et al. (2020). Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 - United States, February 12-March 28, 2020. MMWR Morb Mortal Wkly Rep. , 69:382-6.
Deng Y, Liu W, Liu K, Fang YY, Shang J, Zhou L, et al. . (2020). Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: a retrospective study. . Chin Med J , https://doi.org/10.1097/CM9. 0000000000000824.
Franco VD, Morales Chorro L et all. (2021). Mortalidad por COVID-19 asociada a comorbilidades en pacientes del Instituto Salvadoreño del Seguro Social. Alerta, 4(2):DOI:10.5377/alerta.v4i2.10366.
García J. . (2020). Caracterización de casos positivos y sospechosos de COVID-19 con comorbilidades. Finlay. , 10(3).
Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. . ( 2020). Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med., 382(18):1708-20.
Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. (2020). Clinical characteristics of coronavirus disease 2019 in China. . N Engl J Med. , 382(18):1708-20. .
Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, et al. (2020). Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol, https://doi.org/10.1001/jamaneurol.2020.1127.
Plasencia M. (2020). Comorbilidades y gravedad clínica de la COVID-19: revisión sistemática. Revista Habanera de Ciencias Medicas. , 19.
Red Nacional de Vigilancia Epidemiológica (RENAVE). (2020). Informe sobre la situación de COVID-19 en España. España: Red Nacional de Vigilancia Epidemiológica (RENAVE), https://www.isciii.es/QueHacemos/Servicios/VigilanciaSaludPublicaRENAVE/EnfermedadesTransmisibles/Documents/INFORMES/InformesCOVID-19/InformeNo21Situaci%C3%B3ndeCOVID-19enEspa%C3%B1a%20a%2006deabrilde2020.pdf.
Ruiz Inca P. (2020). Evolución de la enfermedad por coronavirus (COVID-19) en Ecuador. Revista Cientifica de la Facultad de Salud Publica de la Escuela Superior Politecnica de Chimborazo., 11(1).
Stasi C. (2020). Tratamiento para COVID 19; descripcion general. European Journal of Pharmacology. , 889(1).
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. (2020). Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus and infected pneumonia in Wuhan, China. JAMA, Disponible en: https://doi.org/10.1001/jama.2020. 1585 .
Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY, Loh J, et al. (2020). Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. . JAMA , https://doi.org/10.1001/jama.2020.3204.
Zhang JJ, Dong X, Cao YY, Yuan YD, Yang YB, Yan YQ, et al. . (2020). Clinical characteristics of 140 patients infected by SARSCoV-2 in Wuhan, China. . Allergy , https://doi.org/10.1111/ all.14238.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. . (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. , 395:1054-62.
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Revista Científica Arbitrada Multidisciplinaria PENTACIENCIAS - ISSN 2806-5794.

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

